The basis for non-canonical ROK family function in the N-acetylmannosamine kinase from the pathogen Staphylococcus aureus

In environments where glucose is limited, some pathogenic bacteria metabolize host-derived sialic acid as a nutrient source. N-Acetylmannosamine kinase (NanK) is the second enzyme of the bacterial sialic acid import and degradation pathway and adds phosphate to N-acetylmannosamine using ATP to prime...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:J Biol Chem
Main Authors: Coombes, David, Davies, James S., Newton-Vesty, Michael C., Horne, Christopher R., Setty, Thanuja G., Subramanian, Ramaswamy, Moir, James W. B., Friemann, Rosmarie, Panjikar, Santosh, Griffin, Michael D. W., North, Rachel A., Dobson, Renwick C. J.
Format: Artigo
Jezik:Inglês
Izdano: American Society for Biochemistry and Molecular Biology 2020
Teme:
Protein Structure and Folding
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC7062169/
https://ncbi.nlm.nih.gov/pubmed/31949045
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA119.010526
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