Metabolite identification, tissue distribution, excretion and preclinical pharmacokinetic studies of ET-26-HCl, a new analogue of etomidate

ET-26-HCl, a novel anaesthetic agent with promising pharmacological properties, lacks extensive studies on pharmacokinetics and disposition in vitro and in vivo. In this study, we investigated the metabolic stability, metabolite production and plasma protein binding (PPB) of ET-26-HCl along with its...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:R Soc Open Sci
Egile Nagusiak: Yu, Lu, Chen, Xu, Zhang, Wen Sheng, Zheng, Liang, Xu, Wen Wen, Xu, Ming Yu, Jiang, Xue Hua, Wang, Ling
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: The Royal Society 2020
Gaiak:
Chemistry
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC7062083/
https://ncbi.nlm.nih.gov/pubmed/32257329
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1098/rsos.191666
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