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sRNA/L1 retrotransposition: using siRNAs and miRNAs to expand the applications of the cell culture-based LINE-1 retrotransposition assay

The cell culture-based retrotransposition reporter assay has been (and is) an essential tool for the study of vertebrate Long INterspersed Elements (LINEs). Developed more than 20 years ago, this assay has been instrumental in characterizing the role of LINE-encoded proteins in retrotransposition, u...

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Detalles Bibliográficos
Publicado en:Philos Trans R Soc Lond B Biol Sci
Main Authors: Tristan-Ramos, Pablo, Morell, Santiago, Sanchez, Laura, Toledo, Belen, Garcia-Perez, Jose L., Heras, Sara R.
Formato: Artigo
Idioma:Inglês
Publicado: The Royal Society 2020
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7061984/
https://ncbi.nlm.nih.gov/pubmed/32075559
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1098/rstb.2019.0346
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