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Ultrafast Oxime Formation Enables Efficient Fluorescence Light-up Measurement of DNA Base Excision

DNA glycosylases constitute a biologically and biomedically important group of DNA repair enzymes responsible for initiating base excision repair (BER). Measuring their activities can be useful for studying the mechanisms DNA damage and repair and for practical applications in cancer diagnosis and d...

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Bibliografiske detaljer
Udgivet i:J Am Chem Soc
Main Authors: Wilson, David L., Kool, Eric T.
Format: Artigo
Sprog:Inglês
Udgivet: 2019
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7061905/
https://ncbi.nlm.nih.gov/pubmed/31774658
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jacs.9b09812
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