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Ultrafast Oxime Formation Enables Efficient Fluorescence Light-up Measurement of DNA Base Excision

DNA glycosylases constitute a biologically and biomedically important group of DNA repair enzymes responsible for initiating base excision repair (BER). Measuring their activities can be useful for studying the mechanisms DNA damage and repair and for practical applications in cancer diagnosis and d...

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Detalhes bibliográficos
Publicado no:J Am Chem Soc
Main Authors: Wilson, David L., Kool, Eric T.
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7061905/
https://ncbi.nlm.nih.gov/pubmed/31774658
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jacs.9b09812
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