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Deletion of p16 prevents estrogen deficiency-induced osteoporosis by inhibiting oxidative stress and osteocyte senescence

To investigate whether p16 deletion can prevent osteoporosis caused by estrogen deficiency, we first confirmed that p16 protein expression levels were significantly up-regulated in bony tissue of ovariectomized (OVX) wild-type mice. Eight-week-old wild-type and p16(-/-) mice were then sham-operated...

תיאור מלא

שמור ב:
מידע ביבליוגרפי
הוצא לאור ב:Am J Transl Res
Main Authors: Li, Jie, Karim, Muhammad Amin, Che, Hui, Geng, Qinghe, Miao, Dengshun
פורמט: Artigo
שפה:Inglês
יצא לאור: e-Century Publishing Corporation 2020
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC7061825/
https://ncbi.nlm.nih.gov/pubmed/32194914
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