Detection of IDH1 and TERT promoter mutations with droplet digital PCR in diffuse gliomas

Abstract: Mutations in isocitrate dehydrogenase (IDH) and telomerase reverse transcriptase promoter (TERTp) exert a far-reaching influence on clinicopathologic diagnosis and prognosis of glioma. Traditional approaches, such as Sanger sequencing and ARMS, lack sensitivity due to tumor heterogeneity a...

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Detalhes bibliográficos
Publicado no:Int J Clin Exp Pathol
Main Authors: Ge, Jia, Liu, Michael Y, Li, Lei, Deng, Qing, Liu, Feng, Luo, Ying, Wang, Lihong, Yao, Guangyin, Zhu, Dandan, Lu, Huimin, Liang, Mei, Deng, Song, Zhou, Rong, Luo, Tao
Formato: Artigo
Idioma:Inglês
Publicado em: e-Century Publishing Corporation 2020
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7061806/
https://ncbi.nlm.nih.gov/pubmed/32211103
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