Molecular diagnosis of diffuse glioma using a chip-based digital PCR system to analyze IDH, TERT, and H3 mutations in the cerebrospinal fluid

PURPOSE: Conventional genetic analyzers require surgically obtained tumor tissues to confirm the molecular diagnosis of diffuse glioma. Recent technical breakthroughs have enabled increased utilization of cell-free tumor DNA (ctDNA) in body fluids as a reliable resource for molecular diagnosis in va...

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Vydáno v:J Neurooncol
Hlavní autoři: Fujioka, Yutaka, Hata, Nobuhiro, Akagi, Yojiro, Kuga, Daisuke, Hatae, Ryusuke, Sangatsuda, Yuhei, Michiwaki, Yuhei, Amemiya, Takeo, Takigawa, Kosuke, Funakoshi, Yusuke, Sako, Aki, Iwaki, Toru, Iihara, Koji, Mizoguchi, Masahiro
Médium: Artigo
Jazyk:Inglês
Vydáno: Springer US 2021
Témata:
Laboratory Investigation
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7910241/
https://ncbi.nlm.nih.gov/pubmed/33417137
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11060-020-03682-7
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