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Histone demethylase KDM4C activates HIF1α/VEGFA signaling through the costimulatory factor STAT3 in NSCLC

Tumor development is accompanied by high hypoxia and a dense network of immature vessels. The hypoxia-inducible factor/vascular endothelial growth factor (HIF/VEGF) signaling pathway is activated in various solid tumors. It is thought that HIF/VEGF signaling activation results from intratumoral hypo...

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Bibliografske podrobnosti
izdano v:Am J Cancer Res
Main Authors: Wu, Xiaowei, Deng, Yu, Zu, Yukun, Yin, Jin
Format: Artigo
Jezik:Inglês
Izdano: e-Century Publishing Corporation 2020
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC7061751/
https://ncbi.nlm.nih.gov/pubmed/32195022
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