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Microfluidic nutrient gradient–based three-dimensional chondrocyte culture-on-a-chip as an in vitro equine arthritis model

In this work, we describe a microfluidic three-dimensional (3D) chondrocyte culture mimicking in vivo articular chondrocyte morphology, cell distribution, metabolism, and gene expression. This has been accomplished by establishing a physiologic nutrient diffusion gradient across the simulated matrix...

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Detalhes bibliográficos
Publicado no:Mater Today Bio
Main Authors: Rosser, J., Bachmann, B., Jordan, C., Ribitsch, I., Haltmayer, E., Gueltekin, S., Junttila, S., Galik, B., Gyenesei, A., Haddadi, B., Harasek, M., Egerbacher, M., Ertl, P., Jenner, F.
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7061638/
https://ncbi.nlm.nih.gov/pubmed/32159153
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.mtbio.2019.100023
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