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Poly(1-vinylimidazole) polyplexes as novel therapeutic gene carriers for lung cancer therapy

The present work explores the ability of poly(1-vinylimidazole) (PVI) to complex small interfering RNA (siRNA) silencing vascular endothelial growth factor (VEGF) and the in vitro efficiency of the formed complexes in A549 lung cancer cells. The polyplex formed was found to exhibit 66% complexation...

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Vydáno v:Beilstein J Nanotechnol
Hlavní autoři: Kandasamy, Gayathri, Danilovtseva, Elena N, Annenkov, Vadim V, Krishnan, Uma Maheswari
Médium: Artigo
Jazyk:Inglês
Vydáno: Beilstein-Institut 2020
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7061483/
https://ncbi.nlm.nih.gov/pubmed/32190532
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3762/bjnano.11.26
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