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Poly(1-vinylimidazole) polyplexes as novel therapeutic gene carriers for lung cancer therapy
The present work explores the ability of poly(1-vinylimidazole) (PVI) to complex small interfering RNA (siRNA) silencing vascular endothelial growth factor (VEGF) and the in vitro efficiency of the formed complexes in A549 lung cancer cells. The polyplex formed was found to exhibit 66% complexation...
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| Veröffentlicht in: | Beilstein J Nanotechnol |
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| Hauptverfasser: | , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Beilstein-Institut
2020
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7061483/ https://ncbi.nlm.nih.gov/pubmed/32190532 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3762/bjnano.11.26 |
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