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Design of Oligonucleotide Carriers: Importance of Polyamine Chain Length

Amine containing polymers are extensively studied as special carriers for short-chain RNA (13–25 nucleotides), which are applied as gene silencing agents in gene therapy of various diseases including cancer. Elaboration of the oligonucleotide carriers requires knowledge about peculiarities of the ol...

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Dettagli Bibliografici
Pubblicato in:Polymers (Basel)
Autori principali: Annenkov, Vadim V., Krishnan, Uma Maheswari, Pal’shin, Viktor A., Zelinskiy, Stanislav N., Kandasamy, Gayathri, Danilovtseva, Elena N.
Natura: Artigo
Lingua:Inglês
Pubblicazione: MDPI 2018
Soggetti:
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6401700/
https://ncbi.nlm.nih.gov/pubmed/30961222
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/polym10121297
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