The impact of ultraviolet- and infrared-based laser microdissection technology on phosphoprotein detection in the laser microdissection-reverse phase protein array workflow

Reversible protein phosphorylation represents a key mechanism by which signals are transduced in eukaryotic cells. Dysregulated phosphorylation is also a hallmark of carcinogenesis and represents key drug targets in the precision medicine space. Thus, methods that preserve phosphoprotein integrity i...

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Bibliografiske detaljer
Udgivet i:Clin Proteomics
Main Authors: Hunt, Allison L., Pierobon, Mariaelena, Baldelli, Elisa, Oliver, Julie, Mitchell, Dave, Gist, Glenn, Bateman, Nicholas W., Larry Maxwell, G., Petricoin, Emanuel F., Conrads, Thomas P.
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2020
Fag:
Research
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7061469/
https://ncbi.nlm.nih.gov/pubmed/32165870
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12014-020-09272-z
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