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Impact of Upfront Cellular Enrichment by Laser Capture Microdissection on Protein and Phosphoprotein Drug Target Signaling Activation Measurements in Human Lung Cancer: Implications for Personalized Medicine
PURPOSE: The aim of this study was to evaluate whether upfront cellular enrichment via laser capture microdissection is necessary for accurately quantifying predictive biomarkers in non-small cell lung cancer tumors. EXPERIMENTAL DESIGN: Fifteen snap frozen surgical biopsies were analyzed. Whole tis...
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| Publicado no: | Proteomics Clin Appl |
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| Main Authors: | , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4547918/ https://ncbi.nlm.nih.gov/pubmed/25676683 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/prca.201400056 |
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