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Phosphorylation of Tau and α-Synuclein Induced Neurodegeneration in MPTP Mouse Model of Parkinson’s Disease

PURPOSE: Parkinson’s disease (PD) is the second most common neurodegenerative disease. The α-Synuclein is a major component of Lewy bodies and Lewy neurites, the pathologic hallmark of PD. It is known that α-Synuclein is phosphorylated (p-α-Synuclein) in PD and tau-hyperphosphorylation (p-Tau) is al...

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Bibliografiske detaljer
Udgivet i:Neuropsychiatr Dis Treat
Main Authors: Hu, Shanshan, Hu, Meigui, Liu, Jian, Zhang, Bei, Zhang, Zhen, Zhou, Fiona H, Wang, Liping, Dong, Jianghui
Format: Artigo
Sprog:Inglês
Udgivet: Dove 2020
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7061418/
https://ncbi.nlm.nih.gov/pubmed/32184604
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/NDT.S235562
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