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Understanding the Role of Electron Donors in the Reaction Catalyzed by TsrM, a Cobalamin-Dependent Radical S-Adenosylmethionine Methylase
The cobalamin-dependent radical S-adenosylmethionine (SAM) enzyme TsrM catalyzes the methylation of C2 of L-tryptophan to form 2-methyltryptophan during the biosynthesis of thiostrepton A. Although TsrM is a member of the radical SAM superfamily, unlike all other annotated members, it does not catal...
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| Publicado no: | J Biol Inorg Chem |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7061315/ https://ncbi.nlm.nih.gov/pubmed/31350635 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00775-019-01689-8 |
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