NOTCH3 T6746C and TP53 P72R Polymorphisms Are Associated with the Susceptibility to Diffuse Cutaneous Systemic Sclerosis

Introduction. NOTCH pathway and TP53 protein are involved in the development of fibrosis and autoimmune disorders, respectively. The aim of this study was to evaluate the role of single nucleotide polymorphisms (SNPs) of NOTCH3 and TP53 genes and serum anti-TP53 antibodies with the susceptibility, c...

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Publicado en:Biomed Res Int
Autores principales: Zmorzyński, Szymon, Wojcierowska-Litwin, Magdalena, Kowal, Małgorzata, Michalska-Jakubus, Małgorzata, Styk, Wojciech, Filip, Agata Anna, Walecka, Irena, Krasowska, Dorota
Formato: Artigo
Lenguaje:Inglês
Publicado: Hindawi 2020
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Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC7060860/
https://ncbi.nlm.nih.gov/pubmed/32185220
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2020/8465971
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