NOTCH3 T6746C and TP53 P72R Polymorphisms Are Associated with the Susceptibility to Diffuse Cutaneous Systemic Sclerosis

Introduction. NOTCH pathway and TP53 protein are involved in the development of fibrosis and autoimmune disorders, respectively. The aim of this study was to evaluate the role of single nucleotide polymorphisms (SNPs) of NOTCH3 and TP53 genes and serum anti-TP53 antibodies with the susceptibility, c...

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Detalhes bibliográficos
Publicado no:Biomed Res Int
Main Authors: Zmorzyński, Szymon, Wojcierowska-Litwin, Magdalena, Kowal, Małgorzata, Michalska-Jakubus, Małgorzata, Styk, Wojciech, Filip, Agata Anna, Walecka, Irena, Krasowska, Dorota
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi 2020
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7060860/
https://ncbi.nlm.nih.gov/pubmed/32185220
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2020/8465971
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