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The wmN1 Enhancer Region of the Mouse Myelin Proteolipid Protein Gene (mPlp1) is Indispensable for Expression of an mPlp1-lacZ Transgene in both the CNS and PNS

The myelin proteolipid protein gene (PLP1) encodes the most abundant protein in CNS myelin. Expression of the gene must be strictly regulated, as evidenced by human X-linked leukodystrophies resulting from variations in PLP1 copy number, including elevated dosages as well as deletions. Recently, we...

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Vydáno v:Neurochem Res
Hlavní autoři: Patyal, Pankaj, Kockara, Neriman T., Wight, Patricia A.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2019
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7060809/
https://ncbi.nlm.nih.gov/pubmed/31782102
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11064-019-02919-w
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