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The wmN1 Enhancer Region in Intron 1 Is Required for Expression of Human PLP1
The myelin proteolipid protein gene (PLP1) encodes the most abundant protein present in myelin from the central nervous system (CNS). Its expression must be tightly controlled as evidenced by mutations that alter PLP1 dosage; both overexpression (elevated PLP1 copy number) and lack thereof (PLP1 del...
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| Pubblicato in: | Glia |
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| Autori principali: | , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2018
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6201313/ https://ncbi.nlm.nih.gov/pubmed/29683207 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/glia.23339 |
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