Microglia are Indispensable for Synaptic Plasticity in the Spinal Dorsal Horn and Chronic Pain

Spinal long-term potentiation (LTP) at C-fiber synapses is hypothesized to underlie chronic pain. However, the causal link between spinal LTP and chronic pain is still lacking. Here we report that high frequency stimulation (HFS, 100 Hz, 10 V) of the mouse sciatic nerve reliably induces spinal LTP w...

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書誌詳細
出版年:Cell Rep
主要な著者: Zhou, Li-Jun, Peng, Jiyun, Xu, Ya-Nan, Zeng, Wei-Jie, Zhang, Jun, Wei, Xiao, Mai, Chun-Lin, Lin, Zhen-Jia, Liu, Yong, Murugan, Madhuvika, Eyo, Ukpong B., Umpierre, Anthony D., Xin, Wen-Jun, Chen, Tao, Li, Mingtao, Wang, Hui, Richardson, Jason R., Tan, Zhi, Liu, Xian-Guo, Wu, Long-Jun
フォーマット: Artigo
言語:Inglês
出版事項: 2019
主題:
Article
オンライン･アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC7060767/
https://ncbi.nlm.nih.gov/pubmed/31242418
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2019.05.087
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