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Natural variation in DNA methylation homeostasis and the emergence of epialleles
In plants and mammals, DNA methylation plays a critical role in transcriptional silencing by delineating heterochromatin from transcriptionally active euchromatin. A homeostatic balance between heterochromatin and euchromatin is essential to genomic stability. This is evident in many diseases and mu...
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| Udgivet i: | Proc Natl Acad Sci U S A |
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| Main Authors: | , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
National Academy of Sciences
2020
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7060739/ https://ncbi.nlm.nih.gov/pubmed/32071208 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1918172117 |
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