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Contribution of anti-inflammatory and anti-virulence effects of azithromycin in the treatment of experimental Staphylococcus aureus keratitis

BACKGROUND: We aimed to demonstrate the contribution of anti-inflammatory and anti-virulence effects of azithromycin (AZM) in ocular surface infection treatment. METHODS: Staphylococcus aureus was injected into the corneal stroma of rabbits to induce keratitis. AZM at concentrations of 0.01, 0.1, an...

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Detalhes bibliográficos
Publicado no:BMC Ophthalmol
Main Authors: Ikemoto, Kana, Kobayashi, Shinya, Haranosono, Yu, Kozai, Seiko, Wada, Tomoyuki, Tokushige, Hideki, Kawamura, Akio
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7060554/
https://ncbi.nlm.nih.gov/pubmed/32143675
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12886-020-01358-4
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