NOP receptor antagonism reduces alcohol drinking in male and female rats through mechanisms involving the central amygdala and ventral tegmental area

BACKGROUND AND PURPOSE: Nociceptin/orphanin FQ (N/OFQ) peptide and its cognate receptor (NOP) are widely expressed in mesolimbic brain regions where they play an important role in modulating reward and motivation. Early evidence suggested that NOP receptor activation attenuates the rewarding effects...

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Библиографические подробности
Опубликовано в: :Br J Pharmacol
Главные авторы: Borruto, Anna Maria, Fotio, Yannick, Stopponi, Serena, Brunori, Gloria, Petrella, Michele, Caputi, Francesca Felicia, Romualdi, Patrizia, Candeletti, Sanzio, Narendran, Rajesh, Rorick‐Kehn, Linda M., Ubaldi, Massimo, Weiss, Friedbert, Ciccocioppo, Roberto
Формат: Artigo
Язык:Inglês
Опубликовано: John Wiley and Sons Inc. 2020
Предметы:
Research Papers
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC7060370/
https://ncbi.nlm.nih.gov/pubmed/31713848
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bph.14915
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