NOP receptor antagonism reduces alcohol drinking in male and female rats through mechanisms involving the central amygdala and ventral tegmental area

BACKGROUND AND PURPOSE: Nociceptin/orphanin FQ (N/OFQ) peptide and its cognate receptor (NOP) are widely expressed in mesolimbic brain regions where they play an important role in modulating reward and motivation. Early evidence suggested that NOP receptor activation attenuates the rewarding effects...

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Dades bibliogràfiques
Publicat a:Br J Pharmacol
Autors principals: Borruto, Anna Maria, Fotio, Yannick, Stopponi, Serena, Brunori, Gloria, Petrella, Michele, Caputi, Francesca Felicia, Romualdi, Patrizia, Candeletti, Sanzio, Narendran, Rajesh, Rorick‐Kehn, Linda M., Ubaldi, Massimo, Weiss, Friedbert, Ciccocioppo, Roberto
Format: Artigo
Idioma:Inglês
Publicat: John Wiley and Sons Inc. 2020
Matèries:
Research Papers
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7060370/
https://ncbi.nlm.nih.gov/pubmed/31713848
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bph.14915
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