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Synaptamide activates the adhesion GPCR GPR110 (ADGRF1) through GAIN domain binding
Adhesion G protein-coupled receptors (aGPCR) are characterized by a large extracellular region containing a conserved GPCR-autoproteolysis-inducing (GAIN) domain. Despite their relevance to several disease conditions, we do not understand the molecular mechanism by which aGPCRs are physiologically a...
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| Publicado en: | Commun Biol |
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| Main Authors: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
Nature Publishing Group UK
2020
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7060178/ https://ncbi.nlm.nih.gov/pubmed/32144388 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s42003-020-0831-6 |
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