Bisphenol A induces coronary endothelial cell necroptosis by activating RIP3/CamKII dependent pathway

Epidemiological studies link long term exposure to xenoestrogen Bisphenol-A to adverse cardiovascular effects. Our previous results show that BPA induces hypertension by a mechanism involving CamKII activation and increased redox stress caused by eNOS uncoupling. Recently, CamKII sustained activatio...

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Publicat a:Sci Rep
Autors principals: Reventun, P., Sanchez-Esteban, S., Cook, A., Cuadrado, I., Roza, C., Moreno-Gomez-Toledano, R., Muñoz, C., Zaragoza, C., Bosch, R. J., Saura, M.
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group UK 2020
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7060177/
https://ncbi.nlm.nih.gov/pubmed/32144343
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-61014-1
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