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N-acetyltransferase 2 acetylator genotype-dependent N-acetylation of 4-aminobiphenyl in cryopreserved human hepatocytes
Arylamine N-acetyltransferases (NATs) are xenobiotic metabolizing enzymes responsible for detoxification of many drugs and carcinogens. Two NAT proteins (NAT1 and NAT2) are expressed in humans and they both N-acetylate aromatic amine carcinogens such as 4-aminobiphenyl (ABP). Arylamines such as ABP...
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| Publié dans: | Pharmacogenet Genomics |
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| Auteurs principaux: | , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
2020
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7060095/ https://ncbi.nlm.nih.gov/pubmed/31895247 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/FPC.0000000000000394 |
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