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N-acetyltransferase 2 acetylator genotype-dependent N-acetylation of 4-aminobiphenyl in cryopreserved human hepatocytes

Arylamine N-acetyltransferases (NATs) are xenobiotic metabolizing enzymes responsible for detoxification of many drugs and carcinogens. Two NAT proteins (NAT1 and NAT2) are expressed in humans and they both N-acetylate aromatic amine carcinogens such as 4-aminobiphenyl (ABP). Arylamines such as ABP...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
में प्रकाशित:Pharmacogenet Genomics
मुख्य लेखकों: Habil, Mariam R., Doll, Mark A., Hein, David W.
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: 2020
विषय:
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC7060095/
https://ncbi.nlm.nih.gov/pubmed/31895247
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/FPC.0000000000000394
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