Folate-Mediated Targeted Delivery of siPLK1 by Leucine-Bearing Polyethylenimine

BACKGROUND: siRNA-mediated polo-like kinase 1 (PLK1) silencing has been proposed as a promising therapeutic method for multiple cancers. However, the clinic application of this method is still hindered by the low specific delivery of siPLK1 to desired tumor lesions. Herein, folate (FA)-modified and...

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Detaylı Bibliyografya
Yayımlandı:Int J Nanomedicine
Asıl Yazarlar: Hou, Lu, Song, Zheyu, Xu, Zhonghang, Wu, Yuanyu, Shi, Wei
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Dove 2020
Konular:
Original Research
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC7060029/
https://ncbi.nlm.nih.gov/pubmed/32184594
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/IJN.S227289
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