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Exploring the role of RRM domains and conserved aromatic residues in RGG motif  of eIF4G-binding translation repressor protein Sbp1

Background: RNA binding proteins play crucial role in determining if a given mRNA will be translated, stored, or degraded. Sbp1 is an RGG-motif containing protein that is implicated in affecting mRNA decapping and translation. Sbp1 represses translation by binding eIF4G1 through its RGG-motif and ac...

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Detalhes bibliográficos
Publicado no:Wellcome Open Res
Main Authors: Bhatter, Nupur, Iyyappan, Rajan, Mohanan, Gayatri, Rajyaguru, Purusharth I
Formato: Artigo
Idioma:Inglês
Publicado em: F1000 Research Limited 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7059846/
https://ncbi.nlm.nih.gov/pubmed/32175478
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.12688/wellcomeopenres.14709.3
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