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RGG-motif self-association regulates eIF4G-binding translation repressor protein Scd6

Regulation of mRNA translation plays a key role in the control of gene expression. Scd6, a conserved RGG-motif containing protein represses translation by binding to translation initiation factor eIF4G1. Here we report that Scd6 binds itself in RGG-motif dependent manner and self-association regulat...

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Vydáno v:RNA Biol
Hlavní autoři: Poornima, Gopalakrishna, Mythili, Ravishankar, Nag, Priyabrata, Parbin, Sabnam, Verma, Praveen Kumar, Hussain, Tanweer, Rajyaguru, Purusharth I
Médium: Artigo
Jazyk:Inglês
Vydáno: Taylor & Francis 2019
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6693564/
https://ncbi.nlm.nih.gov/pubmed/31157589
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15476286.2019.1621623
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