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Mendelian Randomization Identifies CpG Methylation Sites With Mediation Effects for Genetic Influences on BMD in Peripheral Blood Monocytes

Osteoporosis is mainly characterized by low bone mineral density (BMD) and is an increasingly serious public health concern. DNA methylation is a major epigenetic mechanism that may contribute to the variation in BMD and may mediate the effects of genetic and environmental factors of osteoporosis. I...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:Front Genet
Main Authors: Yu, Fangtang, Qiu, Chuan, Xu, Chao, Tian, Qing, Zhao, Lan-Juan, Wu, Li, Deng, Hong-Wen, Shen, Hui
Format: Artigo
Jezik:Inglês
Izdano: Frontiers Media S.A. 2020
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC7059767/
https://ncbi.nlm.nih.gov/pubmed/32180791
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fgene.2020.00060
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