Mendelian Randomization Identifies CpG Methylation Sites With Mediation Effects for Genetic Influences on BMD in Peripheral Blood Monocytes

Osteoporosis is mainly characterized by low bone mineral density (BMD) and is an increasingly serious public health concern. DNA methylation is a major epigenetic mechanism that may contribute to the variation in BMD and may mediate the effects of genetic and environmental factors of osteoporosis. I...

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Detalles Bibliográficos
Publicado en:Front Genet
Main Authors: Yu, Fangtang, Qiu, Chuan, Xu, Chao, Tian, Qing, Zhao, Lan-Juan, Wu, Li, Deng, Hong-Wen, Shen, Hui
Formato: Artigo
Idioma:Inglês
Publicado: Frontiers Media S.A. 2020
Assuntos:
Genetics
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7059767/
https://ncbi.nlm.nih.gov/pubmed/32180791
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fgene.2020.00060
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