Amentoflavone Attenuates Clostridium perfringens Gas Gangrene by Targeting Alpha-Toxin and Perfringolysin O

Clostridium perfringens (C. perfringens) type A strains are the main cause of gas gangrene in humans and animals. Treatment of this lethal disease is limited, and the prognosis is not good. Alpha-toxin (CPA) and perfringolysin O (PFO) secreted by C. perfringens play irreplaceable roles in cytotoxici...

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Publicado en:Front Pharmacol
Autores principales: Liu, Shui, Yang, Xiaofeng, Zhang, Hong, Zhang, Jian, Zhou, Yonglin, Wang, Tingting, Hu, Naiyu, Deng, Xuming, Bai, Xiaoxue, Wang, Jianfeng
Formato: Artigo
Lenguaje:Inglês
Publicado: Frontiers Media S.A. 2020
Materias:
Pharmacology
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC7059699/
https://ncbi.nlm.nih.gov/pubmed/32180727
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2020.00179
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