Evidence for a novel overlapping coding sequence in POLG initiated at a CUG start codon

BACKGROUND: POLG, located on nuclear chromosome 15, encodes the DNA polymerase γ(Pol γ). Pol γ is responsible for the replication and repair of mitochondrial DNA (mtDNA). Pol γ is the only DNA polymerase found in mitochondria for most animal cells. Mutations in POLG are the most common single-gene c...

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Vydáno v:BMC Genet
Hlavní autoři: Khan, Yousuf A., Jungreis, Irwin, Wright, James C., Mudge, Jonathan M., Choudhary, Jyoti S., Firth, Andrew E., Kellis, Manolis
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2020
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Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7059407/
https://ncbi.nlm.nih.gov/pubmed/32138667
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12863-020-0828-7
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