Genetic barcoding reveals clonal dominance in iPSC-derived mesenchymal stromal cells

BACKGROUND: The use of mesenchymal stromal cells (MSCs) for research and clinical application is hampered by cellular heterogeneity and replicative senescence. Generation of MSC-like cells from induced pluripotent stem cells (iPSCs) may circumvent these limitations, and such iPSC-derived MSCs (iMSCs...

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Publicat a:Stem Cell Res Ther
Autors principals: Hollmann, Jonathan, Brecht, Johanna, Goetzke, Roman, Franzen, Julia, Selich, Anton, Schmidt, Marco, Eipel, Monika, Ostrowska, Alina, Hapala, Jan, Fernandez-Rebollo, Eduardo, Müller-Newen, Gerhard, Rothe, Michael, Eggermann, Thomas, Zenke, Martin, Wagner, Wolfgang
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2020
Matèries:
Research
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7059393/
https://ncbi.nlm.nih.gov/pubmed/32138773
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13287-020-01619-5
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