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Depletion of CD4 T cells provides therapeutic benefits in aged mice after ischemic stroke

T-lymphocytes have a multifaceted role in ischemic stroke, but the majority of studies have been conducted in young mice, which may limit the translational value of these findings. Previous studies have shown that aging results in T cell dysfunction, leading to enhanced production of pro-inflammator...

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Dades bibliogràfiques
Publicat a:Exp Neurol
Autors principals: Harris, Nia M., Roy-o’Reilly, Meaghan, Ritzel, Rodney M., Holmes, Aleah, Sansing, Lauren H., O’Keefe, Lena M., McCullough, Louise D., Chauhan, Anjali
Format: Artigo
Idioma:Inglês
Publicat: 2020
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7059209/
https://ncbi.nlm.nih.gov/pubmed/31954116
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.expneurol.2020.113202
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