Depletion of CD4 T cells provides therapeutic benefits in aged mice after ischemic stroke

T-lymphocytes have a multifaceted role in ischemic stroke, but the majority of studies have been conducted in young mice, which may limit the translational value of these findings. Previous studies have shown that aging results in T cell dysfunction, leading to enhanced production of pro-inflammator...

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Veröffentlicht in:Exp Neurol
Hauptverfasser: Harris, Nia M., Roy-o’Reilly, Meaghan, Ritzel, Rodney M., Holmes, Aleah, Sansing, Lauren H., O’Keefe, Lena M., McCullough, Louise D., Chauhan, Anjali
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2020
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7059209/
https://ncbi.nlm.nih.gov/pubmed/31954116
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.expneurol.2020.113202
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