miR‐181a negatively modulates synaptic plasticity in hippocampal cultures and its inhibition rescues memory deficits in a mouse model of Alzheimer’s disease

MicroRNAs play a pivotal role in rapid, dynamic, and spatiotemporal modulation of synaptic functions. Among them, recent emerging evidence highlights that microRNA‐181a (miR‐181a) is particularly abundant in hippocampal neurons and controls the expression of key plasticity‐related proteins at synaps...

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Detalhes bibliográficos
Publicado no:Aging Cell
Main Authors: Rodriguez‐Ortiz, Carlos J., Prieto, Gilberto Aleph, Martini, Alessandra C., Forner, Stefania, Trujillo‐Estrada, Laura, LaFerla, Frank M., Baglietto‐Vargas, David, Cotman, Carl W., Kitazawa, Masashi
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2020
Assuntos:
Original Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7059142/
https://ncbi.nlm.nih.gov/pubmed/32087004
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/acel.13118
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