Impaired AMPA signaling and cytoskeletal alterations induce early synaptic dysfunction in a mouse model of Alzheimer's disease

Alzheimer's disease (AD) is a devastating neurodegenerative disorder that impairs memory and causes cognitive and psychiatric deficits. New evidences indicate that AD is conceptualized as a disease of synaptic failure, although the molecular and cellular mechanisms underlying these defects rema...

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Publicado en:Aging Cell
Autores principales: Baglietto‐Vargas, David, Prieto, Gilberto Aleph, Limon, Agenor, Forner, Stefania, Rodriguez‐Ortiz, Carlos J., Ikemura, Kenji, Ager, Rahasson R., Medeiros, Rodrigo, Trujillo‐Estrada, Laura, Martini, Alessandra C., Kitazawa, Masashi, Davila, Jose C., Cotman, Carl W., Gutierrez, Antonia, LaFerla, Frank M.
Formato: Artigo
Lenguaje:Inglês
Publicado: John Wiley and Sons Inc. 2018
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Original Articles
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6052400/
https://ncbi.nlm.nih.gov/pubmed/29877034
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/acel.12791
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