Impaired AMPA signaling and cytoskeletal alterations induce early synaptic dysfunction in a mouse model of Alzheimer's disease

Alzheimer's disease (AD) is a devastating neurodegenerative disorder that impairs memory and causes cognitive and psychiatric deficits. New evidences indicate that AD is conceptualized as a disease of synaptic failure, although the molecular and cellular mechanisms underlying these defects rema...

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Bibliografski detalji
Izdano u:Aging Cell
Glavni autori: Baglietto‐Vargas, David, Prieto, Gilberto Aleph, Limon, Agenor, Forner, Stefania, Rodriguez‐Ortiz, Carlos J., Ikemura, Kenji, Ager, Rahasson R., Medeiros, Rodrigo, Trujillo‐Estrada, Laura, Martini, Alessandra C., Kitazawa, Masashi, Davila, Jose C., Cotman, Carl W., Gutierrez, Antonia, LaFerla, Frank M.
Format: Artigo
Jezik:Inglês
Izdano: John Wiley and Sons Inc. 2018
Teme:
Original Articles
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6052400/
https://ncbi.nlm.nih.gov/pubmed/29877034
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/acel.12791
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