Formulation and Characterization of Solid Lipid Nanoparticles Loading RF22-c, a Potent and Selective 5-LO Inhibitor, in a Monocrotaline-Induced Model of Pulmonary Hypertension

Pulmonary arterial hypertension (PAH) is a rare but fatal disease characterized by persistent elevated blood pressure in the pulmonary circulation, due to increased resistance to blood flow, through the lungs. Advances in the understanding of the pathobiology of PAH clarify the role of leukotrienes...

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Detalhes bibliográficos
Publicado no:Front Pharmacol
Main Authors: Liparulo, Angela, Esposito, Renata, Santonocito, Debora, Muñoz-Ramírez, Alejandra, Spaziano, Giuseppe, Bruno, Ferdinando, Xiao, Jianbo, Puglia, Carmelo, Filosa, Rosanna, Berrino, Liberato, D'Agostino, Bruno
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2020
Assuntos:
Pharmacology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7059131/
https://ncbi.nlm.nih.gov/pubmed/32180715
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2020.00083
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