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Sialic Acid-Siglec-E Interactions During Pseudomonas aeruginosa Infection of Macrophages Interferes With Phagosome Maturation by Altering Intracellular Calcium Concentrations

Pseudomonas aeruginosa (PA) is commonly associated with nosocomial and chronic infections of lungs. We have earlier demonstrated that an acidic sugar, sialic acid, is present in PA which is recognized and bound by sialic acid binding immunoglobulin type lectins (siglecs) expressed on neutrophils. He...

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Bibliografiske detaljer
Udgivet i:Front Immunol
Main Authors: Mukherjee, Kaustuv, Khatua, Biswajit, Mandal, Chitra
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2020
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7059019/
https://ncbi.nlm.nih.gov/pubmed/32184783
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2020.00332
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