Sialic Acid-Siglec-E Interactions During Pseudomonas aeruginosa Infection of Macrophages Interferes With Phagosome Maturation by Altering Intracellular Calcium Concentrations

Pseudomonas aeruginosa (PA) is commonly associated with nosocomial and chronic infections of lungs. We have earlier demonstrated that an acidic sugar, sialic acid, is present in PA which is recognized and bound by sialic acid binding immunoglobulin type lectins (siglecs) expressed on neutrophils. He...

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Publicado en:Front Immunol
Autores principales: Mukherjee, Kaustuv, Khatua, Biswajit, Mandal, Chitra
Formato: Artigo
Lenguaje:Inglês
Publicado: Frontiers Media S.A. 2020
Materias:
Immunology
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC7059019/
https://ncbi.nlm.nih.gov/pubmed/32184783
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2020.00332
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