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TCR-Like CAR-T Cells Targeting MHC-Bound Minor Histocompatibility Antigens

Minor histocompatibility antigens (mHAgs) in allogeneic hematopoietic stem cell transplantation are highly immunogenic as they are foreign antigens and cause polymorphism between donors and recipients. Adoptive cell therapy with mHAg-specific T cells may be an effective option for therapy against re...

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Detalles Bibliográficos
Publicado en:Front Immunol
Autor Principal: Akatsuka, Yoshiki
Formato: Artigo
Idioma:Inglês
Publicado: Frontiers Media S.A. 2020
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7058980/
https://ncbi.nlm.nih.gov/pubmed/32184779
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2020.00257
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