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Targeting Circulating SINEs and LINEs with DNase I Provides Metastases Inhibition in Experimental Tumor Models

Tumor-associated cell-free DNAs (cfDNAs) are found to play some important roles at different stages of tumor progression; they are involved in the transformation of normal cells and contribute to tumor migration and invasion. DNase I is considered a promising cancer cure, due to its ability to degra...

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Detalhes bibliográficos
Publicado no:Mol Ther Nucleic Acids
Main Authors: Alekseeva, Ludmila A., Sen’kova, Aleksandra V., Zenkova, Marina A., Mironova, Nadezhda L.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Gene & Cell Therapy 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7058713/
https://ncbi.nlm.nih.gov/pubmed/32146418
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.omtn.2020.01.035
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