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Dexmedetomidine Alleviated Endoplasmic Reticulum Stress via Inducing ER-phagy in the Spinal Cord of Neuropathic Pain Model

Studies demonstrated that spinal autophagy was impaired in spinal nerve ligation (SNL) rats. However, the relationship of endoplasmic reticulum (ER) stress and ER-phagy and whether dexmedetomidine (DEX) modulates ER-phagy remain unclear. In this study, male Sprague–Dawley (SD) rats and the SNL anima...

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Detalhes bibliográficos
Publicado no:Front Neurosci
Main Authors: Liu, Yongda, Wang, Shuang, Wang, Zhibin, Ding, Mengmeng, Li, Xingyue, Guo, Jiao, Han, Guang, Zhao, Ping
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7058658/
https://ncbi.nlm.nih.gov/pubmed/32184704
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnins.2020.00090
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