Dexmedetomidine Alleviated Endoplasmic Reticulum Stress via Inducing ER-phagy in the Spinal Cord of Neuropathic Pain Model

Studies demonstrated that spinal autophagy was impaired in spinal nerve ligation (SNL) rats. However, the relationship of endoplasmic reticulum (ER) stress and ER-phagy and whether dexmedetomidine (DEX) modulates ER-phagy remain unclear. In this study, male Sprague–Dawley (SD) rats and the SNL anima...

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書目詳細資料
發表在:Front Neurosci
Main Authors: Liu, Yongda, Wang, Shuang, Wang, Zhibin, Ding, Mengmeng, Li, Xingyue, Guo, Jiao, Han, Guang, Zhao, Ping
格式: Artigo
語言:Inglês
出版: Frontiers Media S.A. 2020
主題:
Neuroscience
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC7058658/
https://ncbi.nlm.nih.gov/pubmed/32184704
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnins.2020.00090
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