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Structure–function analyses of a keratin heterotypic complex identify specific keratin regions involved in intermediate filament assembly

Intermediate filaments (IFs) provide vital mechanical support in a broad array of cell types. Interference with this role causes cell fragility and accounts for a large number of human diseases. Gaining an understanding IF structure is paramount to understanding their function and designing therapeu...

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Bibliografiske detaljer
Udgivet i:Structure
Main Authors: Lee, Chang-Hun, Kim, Min-Sung, Li, Shuang, Leahy, Daniel J., Coulombe, Pierre A.
Format: Artigo
Sprog:Inglês
Udgivet: 2020
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7058483/
https://ncbi.nlm.nih.gov/pubmed/31995743
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.str.2020.01.002
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