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The making and function of CAR cells

Genetically engineered T cells expressing chimeric antigen receptors (CAR) present a new treatment option for patients with cancer. Recent clinical trials of B cell leukemia have demonstrated a response rate of up to 90%. However, CAR cell therapy is frequently accompanied by severe side effects suc...

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Bibliografiske detaljer
Udgivet i:Immunol Lett
Main Authors: Zabel, Maja, Tauber, Peter A., Pickl, Winfried F.
Format: Artigo
Sprog:Inglês
Udgivet: 2019
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7058416/
https://ncbi.nlm.nih.gov/pubmed/31181279
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.imlet.2019.06.002
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