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On Peptides and Altered Peptide Ligands: From Origin, Mode of Action and Design to Clinical Application (Immunotherapy)

T lymphocytes equipped with clonotypic T cell antigen receptors (TCR) recognize immunogenic peptides only when presented in the context of their own major histocompatibility complex (MHC) molecules. Peptide loading to MHC molecules occurs in intracellular compartments (ER for class I and MIIC for cl...

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Detalhes bibliográficos
Publicado no:Int Arch Allergy Immunol
Main Authors: Candia, Martín, Kratzer, Bernhard, Pickl, Winfried F.
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7058415/
https://ncbi.nlm.nih.gov/pubmed/27642756
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1159/000448756
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