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Temporal changes in the gene expression heterogeneity during brain development and aging

Cells in largely non-mitotic tissues such as the brain are prone to stochastic (epi-)genetic alterations that may cause increased variability between cells and individuals over time. Although increased inter-individual heterogeneity in gene expression was previously reported, whether this process st...

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Pubblicato in:Sci Rep
Autori principali: Işıldak, Ulaş, Somel, Mehmet, Thornton, Janet M., Dönertaş, Handan Melike
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group UK 2020
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7058021/
https://ncbi.nlm.nih.gov/pubmed/32139741
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-60998-0
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