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Structural basis of RNA polymerase I pre-initiation complex formation and promoter melting

Transcription of the ribosomal RNA precursor by RNA polymerase (Pol) I is a prerequisite for the biosynthesis of ribosomes in eukaryotes. Compared to Pols II and III, the mechanisms underlying promoter recognition, initiation complex formation and DNA melting by Pol I substantially diverge. Here, we...

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Bibliografiske detaljer
Udgivet i:Nat Commun
Main Authors: Pilsl, Michael, Engel, Christoph
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group UK 2020
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7057995/
https://ncbi.nlm.nih.gov/pubmed/32139698
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-020-15052-y
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